Propalin Syrup for Female Dogs

	Propalin is a drug used to control urinary incontinence which is caused by urethral sphincter mechanism incompetence in neutered bitches. Propalin contains the active ingredient phenylpropanolamine. Phenylpropanolamine is a "sympathomimetic" drug which stimulates alpha adrenergic receptors in nerves. This means that Propalin mimics the sympathetic nervous system, responsible for "flight or fight" as this also causes urine to be retained. Propalin stimulates the alpha adrenergic receptors in the nerves that control the urethra and cause an increase in the pressure that keeps the urethra closed which acts to retain the urine and stop it leaking from the animal.
Doseage and Application: Your vet will detail the dose required for your dog. The manufacturer recommends a dose rate for Propalin is 0.8mg of the active ingredient phenylpropanolamine per kg bodyweight. The concentration of Propalin is 40mg phenylpropanolamine per ml syrup so this equates to 0.1ml Propalin syrup per 5kg of bodyweight. The dose of Propalin is given three times a day by mouth. Propalin is absorbed better and is therefore more effective if given to fasted dogs, on an empty stomach.
Active Constituents: Each ml contains 50mg Phenylpropanolamine Hydrochloride BP
Safety: Propalin can have some side effects, especially at high doses and these are related to over stimulation of the sympathetic nervous system. These include diarrhoea, increased heart rate and blood pressure, restlessness, dizziness and in severe cases, collapse. These are usually reversible when treatment with Propalin is stopped. If you suspect any potential side effects then contact your vet. Propalin should not be given to intact (Non neutered bitches) especially if they are pregnant or lactating. Propalin should be used with care in animals with Diabetes, Cushings, Kidney or Liver disease or any other underlying metabolic disease. In animals under 1 year of age, there can be an anatomical reason for the urinary incontinence and it should be attempted to rule this out before starting treatment with Propalin.

For more information and option to buy link to: www.petmedz.co.nz